1. Preliminary intraoperative validation of the NOL Index, a non-invasive nociception monitor
Ruth Edry, Vasile Recea, Yuri Dikust, Daniel I. Sessler.
Anesthesiology July 2016, Vol.125, 193-203

2. Ability of the Nociception Level (NOL), a multiparameter composite of autonomic signals, to detect noxious stimuli during propofol-remifentanil anesthesia
Chris H. Martini, Martijn Boon, Suzanne J. L. Broens, Evelien F. Hekkelman, Lisanne A. Oudhoff, Anna Willemijn Buddeke, Albert Dahan.
Anesthesiology Sept. 2015, Vol.123, 524-534

3. Monitoring the Nociception Level – A Multi-Parameter Approach
Nir Ben-Israel, Mark Kliger, Galit Zuckerman, Yeshayahu Katz, Ruth Edry.
Journal of Clinical Monitoring and Computing (2013) 27: 659

4. Differentiating between heat pain intensities: the combined effect of multiple autonomic parameters
Treister Roi, Kliger Mark, Zuckerman Galit, Itay Goor Aryeh, Eisenberg Elon.
Pain. 2012 Sept.;153(9):1807-14




1. Assessing pain objectively: the use of physiological markers
Rachel Cowen, Maria Stasiowska, Helen Laycock, Carsten Bantel.
Anaesthesia. 2015 July ;70(7):828-47

2. Acute psychosocial stress reduces pain modulation capabilities in healthy men
Geva Nirit, Pruessner Jens, Defrin Ruth.
Pain. 2014 Nov.;155(11):2418-25

3. Multi-parameter autonomic-based pain assessment: More is more?
Marco L. Loggia, Vitaly Napadow.
PAIN 153 (2012) 1779–1780

4. Objective Assessment of Acute Pain
Helen Laycock, Carsten Bantel.
J Anesth Clin Res 2016, 7:6

5. Physiological Signal Processing for Individualized Anti-nociception Management During General Anesthesia: a Review.
Julien De Jonckheere, Vincent Bonhomme, Mathieu Jeanne, Emmanuel Boselli, Matthias Gruenewald, Regis Logier, Philippe Richebé.
Yearb Med Inform. 2015 Aug 13;10(1):95-101


Abstracts, Poster and Oral Presentations

1. Developing a Monitor Process Perspective.
Dr. Ruth Edry – oral presentation at the 2016 Annual Meeting of the Israeli Society of Anesthesiology, December 2016

2. Quantified Analgesic Effect of Intraoperative 50% N2O Inhalation by the NOL and ANI Nociception Indices
Philippe G. Richebe, Elizabeth Decary, Rami Issa, Sarah Maximos, Louis-Philippe Fortier, Olivier Verdonck.
ASA (American Society of Anesthesiologists), Chicago, IL, USA, 2016

3. NOL index variation after standardized nociceptive stimulus decreases with higher doses of remifentanil
Marco Julien, Elizabeth Décary, Rami Issa, Olivier Verdonck, Louis-Philippe Fortier, Philippe Richebé.
EuroAnesthesia – ESA (European Society of Anaesthesiology). London, UK, 2016

4. Ability of the nociception level, a Multiparameter Composite of Autonomic Signals, to detect noxious stimuli during propofol-remifentanil anesthesia
Chris Martini, Martijn Boon, Albert Dahan.
ASA (American Society of Anesthesiologists), San Diego, USA, Oct. 2015

5. The level of nociception (NOL) in thoracotomy patients with and without epidural analgesia
Laurent Bollag, Srdjan Jelacic, Cynthia Wu, Philippe Richebé.
EFIC Pain Congress, Vienna, Austria, Sept. 2015

6. Validation of nociception monitor – The NOL Index
Ruth Edry, Vasile Recea, Yuri Dikust, Daniel I. Sessler.
EuroAnesthesia  – ESA (European Society of Anaesthesiology), Germany, June 2015 (1AP12-6, page 53)

7. Objective assessment of spinal cord stimulation effectiveness on chronic radicular pain
Nir Ben-Israel, Yariv Amos, Noam Racheli, Mark Kliger, Galit Zuckerman, Roi Treister, Elon Eisenberg.
IASP (International Association for the Study of Pain Annual Meeting), Argentina, Oct. 2014

8. Objective measurement of pain levels in patients with radicular pain treated by spinal cord stimulation
Nir Ben-Israel, Yariv Amos, Mark Kliger, Galit Zuckerman, Erica Suzan, Elon Eisenberg.
AAPM (American Academy of Pain Medicine Annual Meeting), AZ, USA,  Mar. 2014

9. Detection of noxious stimuli during general anesthesia using the NOL index for nociception level
Edry Ruth, Kliger Mark, Zuckerman Galit, Racheli Noam, Katz Yeshayahu, Ben-Israel Nir.
EuroAnesthesia – ESA (European Society of Anaesthesiology), Barcelona, Spain, June 2013

10. Non-linear Multi-Parameter Approach for Evaluation of Nociception Level During General Anesthesia
Ben-Israel Nir, Zuckerman Galit, Kliger Mark, Katz Yeshayahu, Edry Ruth.
STA (Society for Technology in Anesthesia), Phoenix, AZ, Jan. 2013
ASA (American Society of Anesthesiologists), Washington DC, Oct. 2012

11. A combination of multiple autonomic parameters, rather than each parameter alone, yields significant differentiation between heat pain intensities
Roi Treister, Mark Kliger, Galit Zuckerman, Itay Goor Aryeh, Elon Eisenberg.
EFIC  Pain Conference, Germany, 2011

12. Toward automatic pain monitoring: Method for classification of pain level based on statistical processing of multiple non-invasive physiological measures
Roi Treister, Mark Kliger, Galit Zuckerman, Itay Goor Aryeh, Elon Eisenberg.
IPA Conference, Israel, 2010